Draft Genome Sequence of Proteus mirabilis NO-051/03, Representative of a Multidrug-Resistant Clone Spreading in Europe and Expressing the CMY-16 AmpC-Type β-Lactamase

نویسندگان

  • Marco Maria D’Andrea
  • Tommaso Giani
  • Lucia Henrici De Angelis
  • Nagaia Ciacci
  • Marek Gniadkowski
  • Vivi Miriagou
  • Francesca Torricelli
  • Gian Maria Rossolini
چکیده

Proteus mirabilis NO-051/03, representative of a multidrug-resistant clone expressing the CMY-16 AmpC-type β-lactamase and circulating in Europe since 2003, was sequenced by a MiSeq platform using a paired-end approach. The genome was assembled in 100 scaffolds with a total length of 4,197,318 bp. Analysis of the draft genome sequence revealed the presence of several acquired resistance determinants to β-lactams, aminoglycosides, phenicols, tetracyclines, trimethoprim, and sulfonamides, of one plasmid replicon, and of a type I-E clustered regularly interspaced short palindromic repeat (CRISPR)-associated protein (Cas) adaptive immune system.

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عنوان ژورنال:

دوره 4  شماره 

صفحات  -

تاریخ انتشار 2016